In 2003, Pr J.M. François and Pr J.P. Majoral have patented the dendrimer-based DNA microarrays technology for molecular diagnosis. This technology is based on the coating of phosphorus dendrimers on solid supports. This allows covalent linkages of oligonucleotide probes, which greatly optimizes DNA hybridization (i.e.10-fold higher signal than other commercial technologies). From 2003 to 2007, the proof of concept and technological readiness has been demonstrated in several publications.
In 2009, Dr R. Fabre, biologist (Bio Pôle), Pr J.M. François (PFBT, INSA) and Pr J.P. Majoral (LCC, CNRS) decided to found Dendris in order to develop a new generation of in vitro diagnosis (IVD) kits. Therefore, Dendris SAS emerged from a scientific, technical and management cooperation and uses dendrimer-based DNA microarrays technology with an exclusive license from CNRS.
M. Corbarieu and A. Leonard, successful entrepreneurs joined Dendris in 2010, as business manager and member of the guidance and supervision service respectively.
IMPORTANT STEPS TAKEN
Dr Richard Fabre
PhD in pharmacy and biology, expert in molecular biology. Owner of Biopole a medical analysis laboratory. Join INOVIE Group (more than 330 Laboratories in France) in 2017. Member of Medical Laboratory Union board. Author of 20 publications in molecular diagnostic field.
Pr Jean-marie François
Exceptional Class professor and research director in bio-engineering & bio-nanotechnology at LISBP (Laboratoire d’Ingénierie des Systèmes Biologiques et Procédés) INSA-CNRS, Toulouse. Author of 180 publications and owner of 17 patents. He is the bio-engineering expert of Dendris, in charge of Dendrischip design and bioprocess.
Pr Jean-Pierre Majoral
Scientific expert - Chemistry
Honorary research director at CNRS, PhD in Chemistry and worldwide expert in nano-chemistry and dendrimers, author of 733 publications, 7 books and 47 patents. This work is cited in over 23,000 publications.
Co-president and financial director
Co-founder of Silogic in 1989, IT engineering company, a success story company which grew from 12 people at the foundation up to 600 in 2006. At Dendris, he is in charge of contractual and financial matters.
Member of the guidance and supervision service
Founder of Teknimed (company focused on biomaterials) and of BioDendrimers International (leader in dendrimers chemistry). He is a very experienced business man bringing his know-how to Dendris.