In 2003, J.M. François and J.P. Majoral have patented the dendrimer-based DNA microarrays technology for molecular diagnosis. This technology is based on the coating of phosphorus dendrimers on solid supports. This allows covalent linkages of oligonucleotide probes, which greatly optimizes DNA hybridization (i.e.10-fold higher signal than other commercial technologies). From 2003 to 2007, the proof of concept and technological readiness has been demonstrated in several publications.
In 2009, R. Fabre (Bio Pôle), J.M. François (PFBT, INSA) and J.P. Majoral (LCC, CNRS) decided to found Dendris in order to develop a new generation of in vitro diagnosis (IVD) kits. Therefore, Dendris SAS emerged from a scientific, technical and management cooperation and uses dendrimer-based DNA microarrays technology with an exclusive license from CNRS.
Corbarieu and A. Leonard joined Dendris in 2010, as business manager and member of the guidance and supervision service respectively.
IMPORTANT STEPS TAKEN
President and CEO
Phd Richard Fabre
At Dendris in charge of marketing, customers and third parties (government, regulatory authorities) relationship.
Member of the guidance and supervision service
Phd Jean-Pierre Majoral